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  3. Vol. 1 No. 2 (2005): IJPS_Volume 1_Issue 2
  4. Research/Original Articles

Vol. 1 No. 2 (2005)

April 2005

Asthma: Achievements and Questions in Front Asthma: achievements and questions in front

  • Jamshid Salamzadeh

Iranian Journal of Pharmaceutical Sciences, Vol. 1 No. 2 (2005), 1 April 2005 , Page 63-67
https://doi.org/10.22037/ijps.v1.39445 Published: 2005-06-30

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Abstract

Asthma, which is mainly distinguished by airway inflammation and bronchial hyper-responsiveness, is known as one of the most common chronic diseases
worldwide. It also is the most frequent chronic respiratory disorder amongst all age groups. On one side of the asthma story, there are massive investment of time, effort and money, a large number of pharmaceutical and academic research studies, health service modifications and revised guidelines. On the other side, there are unacceptably high, but mostly preventable, morbidity and mortality rates, socio-economic burdens and psychological problems due to asthma. A considerable proportion of doctor’s workload, hospital resources, health utilization costs, days off from school and work are caused by asthma. Our knowledge about this disorder and its complications is still on demand. There are significant questions regarding asthma and its pathophysiology which should be answered. National, regional and local initiatives are needed to be established to help health systems to overcome socio-economic burdens due
to this disease. These could only be done if a clear picture of this respiratory disorder and its management achievements are available. This review article is an
approach to present an image about asthma and its management based on the current understandings of the nature of this disorder.

Keywords:
  • Asthma
  • Epidemiology
  • Risk factors
  • Classification
  • Management
  • IJPS_Volume 1_Issue 2_Pages 63-67

How to Cite

Salamzadeh, J. . (2005). Asthma: Achievements and Questions in Front: Asthma: achievements and questions in front. Iranian Journal of Pharmaceutical Sciences, 1(2), 63–67. https://doi.org/10.22037/ijps.v1.39445
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References

[1] Chung KF, Adcock I. Asthma mechanisms and protocols. New Jersey: Humana Press, 2000; pp.1-29.
[2] Kelly HW. Asthma. In: Koda-Kimbel MA, Young LY, (editors). Applied therapeutics: the clinical use of drugs. 5th ed. Washington: Applied Therapeutics Inc., 1992; pp.15.1 – 15.24.
[3] Hartl D, Greise M, Nicolai T, Zissel G, Prell C, Konstantopoulos N, Gruber R, Reinhardt D, Schendel DJ, Krauss-Etschmann S. Pulmonary chemokines and their receptors differentiate children with asthma and chronic cough. J Aallergy Clin Immunol 2005; 115: 728-36.
[4] Kuepper M, Bratke K, Julius P, Ogawa K, Nagata K, Luttman W, Virchow JC Jr. Increase in killerspecific secretory protein of 37 kDa in bronchoalveolar lavage fluid of allergenchallenged patients with atopic asthma. Clin Exp llergy 2005; 35: 643-9.
[5] Muratov V, Barck C, Bylin G, Kallstorm E, Hallden G, van Hage M, Elvin K, Lundahl J. Aallergen challenge alters intracellular cytokine expression. Scan J Immunol 2005; 62: 161-7.
[6] Schaller MA, Lundy SK, Hhuffnagle GB, Lukacs NW. CD8+ T cell contributions to allergen induced pulmonary inflammation and airway hyperreactivity.
Eur J Immunol 2005; 35: 2061-70.
[7] Evans JF. Cysteinyl leukotriene receptors. Prostaglandins Other Lipid Mediat. 2002; 68- 69: 587-97.
[8] National Hearth, Lung and Blood Institute and World Health Organisation Workshop report: global strategy for asthma management and prevention [Online], 2004 [Accessed 2005 April 04]; aAvailable from: URL: http://www.ginasthma.com/Guidelineitem.asp??l1=2&l2=1&intId=60.
[9] National Asthma Campaign. The national asthma audit. London; 1999/2000.
[10] Murray AB, Morrison BJ. Effect of passive smoking on asthmatic children who have and who have not had atopic dermatitis. Chest 1992; 101: 16-8.
[11] von Mutius E, Fritzsch C, Weiland SK, Roll G, Magnussen H. Prevalence of asthma and allergic disorders among children in united Germany: a descriptive comparison. Br Med J 1992; 305: 1395-9.
[12] Black PN, Sharpe S. Dietary fat and asthma: is there a connection? Eur Respir J 1997; 10: 6-12.
[13] Burney PG, Neild JE, Twort CH, Chinn S, Jones TD, Mitchell WD, Bateman C, Cameron IR. Effect of changing dietary sodium on the airway response to histamine. Thorax 1989; 44: 36-41.
[14] Salamzadeh J, Wong ICK., Hosker H, Chrystyn H. The relationship between the quality of prescribing and practice appointment rates with asthma anagement data in those admitted to hospital due to an acute exacerbation. Respir Med 2005; 99: 735-41.
[15] Adams RJ, Smith BJ, Ruffin, RE. Factors associated with hospital admissions and repeat emergency department visits for adults with asthma. Thorax 2000; 55: 566-73.
[16] Salamzadeh J, Habibi M, Fahimi F, Boroumand B. Astudy of possible predictors associated with hospitalization in 198 asthmatic outpatients refereed to the Labbafi-nezhad university hospital in Tehran. In: Valizadeh H, Azarmi Sh, Ghobe Zarrin N, (editors). 9th Iranian Seminar of Pharmaceutical Sciences. Abstracts of
contributions; Tabriz, Iran, 2004 August 23-26; Tabriz, Iran:. Tabriz University of Medical Sciences; 2004; p. 282.
[17] Coakley AL, Johnson AJ. Inhaled steroids for asthma: a qualitative study exploring patients’ views and the meeting of educational needs within inhaler packaging. Asthma J 1999; 4: 175-8.
[18] O’Callaghan C, Barry P. Delivering inhaled corticosteroids to patients: if side effects are important, why are we so ignorant of the dose inhaled? Br Med J 1999; 318: 410-1.
[19] Clark NM, Gong M. Management of chronic disease by practitioners and patients: are we teaching the wrong things? Br Med J 2000; 320: 572-5.
[20] Stevenson FA. The strategies used by general practitioners when providing information about medicines. Patient Educ Couns 2001; 43: 97-104.
[21] Ordonez GA, Phelan PD, Olinsky A, Robertson CF. Preventable factors in hospital admissions for asthma. Arch Dis Child 1998; 78: 143-7.
[22] Bosley CM, Fosbury JA, Cochrane GM. The psychological factors associated with poor compliance with treatment in asthma. Eur Respir J 1995; 8: 899-904.
[23] FitzGerald JM, Turner MO. Delivering asthma education to special high risk group. Patient Educ Couns 1997; 32: S77-S86.
[24] Gruffydd-Jones K. Compliance: the challenge in asthma management.; London: Miller Freeman UK Ltd. 1998; pp.1-8.
[25] Raherison C, Tunon-De-Lara JM, Vernejoux JM, Taytard A. Practical evaluation of asthma exacerbation self-management in children and adolescents. Respir Med 2000; 94: 1047- 52.
[26] Salamzadeh J, Fahimi F, Habibi M, Boroumand B. Astudy of inhaler technique in asthmatics and its explanatory parameters. In: Valizadeh H, Azarmi Sh, Ghobe Zarrin N, eds. 9th Iranian Seminar of Pharmaceutical Sciences. Abstracts of contributions; 2004 August 23-26; Tabriz, Iran. Tabriz university of Medical Sciences; 2004; pp.283. In: Valizadeh H, Azarmi S, Ghobe Zarrin N, (editors). 9th Iranian Seminar of Pharmaceutical Sciences. Abstracts of contributions; Tabriz, Iran,
2004 August 23-26: Tabriz University of Medical Sciences; p. 283.
[27] Salamzadeh J, Habibi M, Boroumand B. Peak Expiratory Flow Rate (PEFR) in asthmatic patients: what are possible predictors? In: Valizadeh H, Azarmi Sh, Ghobe Zarrin N, eds. 9th Iranian Seminar of Pharmaceutical Sciences. Abstracts of contributions; 2004 August 23-26; Tabriz, Iran. Tabriz university of Medical
Sciences; 2004; p. 278.
[28] Eachus J, Williams M, Chan P, Smith GD, Grainge M, Donovan J, Frankle S. Deprivation and cause specific morbidity: evidence from the Somerset and Avon survey of health. Br Med J 1996; 312, 287-92. [29] Minkovitz CS, Andrews JS, Serwint JR. Rehospitalization of children with asthma. Arch Pediatr Adolesc Med 1999; 153: 727-30.
[30] Majeed A, Bardsley M, Morgan D, O’Sullivan C, Bindman AB. Cross sectional study of primary care groups in London: association of measures of ocioeconomic and health status with hospital admission rates. Br Med J 2000; 321, 1057-60.
[31] Watson JP, Cowen P, Lewis RA. The relationship between asthma admission rates, routes of admission, and socioeconomic deprivation. Eru Respir J 1996; 9: 2087-93.
[32] Salamzadeh J, Patel MG, Wong ICK, Wright DJ, Chrystyn H. Characteristics of general practices with different asthma prescribing. Pharma J (suppl) 2000, 265: R52.
[33] Gottlieb D J, Beiser AS, O’Connor GT. Poverty, race, and medication use are correlates of asthma hospitalization rates. Chest 1995; 108: 28-35.
[34] Finkelstein JA, Brown RW, Schneider LC, Weiss ST, Quintana JM, Goldmann DA, Homer CJ. Quality of care for pre-school children with asthma: the role of social factors and practice setting. Pediatrics 1995; 95: 389-94.
[35] Duran-Tauleria E, Rona RJ, Chinn S, Burney P. Influence of ethnic group on asthma treatment in children in 1990-1: national cross sectional study. Br Med J 1996; 313: 148-52.
[36] Apter AJ, Reisine ST, Affleck G, Barrows E, ZuWallack RL. The influence of demographic and socioeconomic factors on health-related quality of life in asthma. J Allergy Clin Immunol 1999; 103: 72-8.
[37] Gilthorpe MS, Lay-Yee R, Wilson RC, Griffiths RK, Bedi R. Variations in hospitalization rates for asthma among Black and minority ethnic communities. Respir Med 1998; 92: 642-8.
[38] Moudgil, H., Marshall, T. and Honeybourne, T. Asthma education and quality of life in the community: a randomized controlled study to evaluate the impact on white European and Indian subcontinent ethnic groups from socioeconomically deprived areas in Birmingham, UK. Thorax 2000; 55: 177-183.
[39] Salamzadeh J, Patel M, Wong I, Wright D, Chrystyn H. Analysis of the impact of practice characteristics and social deprivation on prescribing quality for asthma. Thorax (suppl.) 1999; 54: A54.
[40] Law MR, Morris JK. Why is mortality higher in poorer areas and in more Northern areas of England and Wales? J Epidemiol Community Health 1998; 52: 344-52.
[41] Hippisley-Cox J, Hardy C, Pringle M, Fielding K, Carlisle R, Chilvers C. The effect of deprivation on variations in general practitioners’ referral rates: cross sectional study of computerized data on new medical and surgical outpatient referrals in Nottinghamshire. Br Med J 1997; 314: 1458 - 61.
[42] Salamzadeh J, Wong ICK, Hosker HSR, Chrystyn H. A logistic regression analysis of predictors for asthma hospital re-admissions. Iranian J Pharma Res (IJPR) 2003; 2: 5-9.
[43] Salamzadeh J, Wong ICK, Hosker HSR, Chrystyn H. A cox regression analysis of covariates for asthma hospital readmissions. J Asthma 2003; 40: 645-52.
[44] Matthews S, Manor O, Power C. Social inequalities in health: are there gender differences? Soc Sci Med 1999; 48: 49-60.
[45] Sexton M, Althuis MD, Santanello N, Hyndman S, Williams R, Schmeidler D. Sex differences in the use of asthma drugs: cross sectional study. Br Med J 1998; 317: 1434-37.
[46] Yuksel N, Ginther S, Man P, Tsuyuki RT. Underuse of inhaled corticosteroids in adults with asthma. Pharmacother 2000; 20: 387-93.
[47] Heard AR, Campbell DA, Ruffin RE, Smith B, Luke CG, Roder DM. Rehospitalization for asthma within 12 months: unequal rates on the basis of gender at two hospitals. Aust N Z J Med 1997; 27: 669-71.
[48] Mitchell EA, Bland JM, Thompson JMD. Risk factors for readmission to hospital for asthma in childhood. Thorax 1994; 49: 33-6.
[49] Prescott E, Lange P, Vestbo J, Jensen G, Schnohr P, Appleyard M, Nyboe J, Grenbaeck M, Nordestgaard B. Effect of gender on hospital admissions for asthma and prevalence of selfreported asthma: a prospective study based on a sample of the general population. Thorax 1997; 52: 287-9.
[50] Langhammer A, Johnsn R, Holmen J, Gulsvik A, Bjermer L. Cigarette smoking gives more respiratory symptoms among women than among men: The Nord-Trondelag health study (HUNT). J Epidemiol Community Health 2000; 54: 917-22.
[51] Siroux V, Pin I, Oryszczyn MP Le Moual N, Kauffmann F. Relationship of active smoking to asthma and asthma severity in the EGEA study. Epidemiological study on the genetics and environment of asthma. Eur Respir J 2000; 15: 470-7.
[52] Eisner MD, Yelin EH, Henke J, Shiboski SC, Blanc PD. Environmental tobacco smoke and adult asthma: the impact of changing exposure status on health outcomes. Am J Respir Crit Care Med 1998; 158: 170-5.
[53] Gurkan F, Ece A, Haspolat K, Derman O, Bosnak M. Predictors for multiple hospital admissions in children with asthma. Can Respir J 2000; 7: 163-6.
[54] Rosas I, McCartney HA, Payne RW, Calderon C, Lacey J, Chapela R, Ruiz-Velazco S. Analysis of the relationship between environmental factors (aeroallergens, air pollution, and weather) and asthma emergency admissions to a hospital in Mexico City. Eur J Allergy Clin Immunol 1998; 53: 394-401.
[55] Miles J, Cayton R, Ayres J. Atopic status in patients with brittle and non-brittle asthma: a case-control study. Clin Exp Allergy 1995; 25: 1074-82.
[56] Sporik R, Platts-Mills TAE, Cogswell JJ. Exposure to house dust mite allergen of children admitted to hospital with asthma. Clin Exp Allergy 1993; 23: 740-6.
[57] Warner JA, Warner JO. Allergen avoidance in childhood asthma. Respir Med 1991; 85: 101-5.
[58] Cassino C, Berger KI, Goldring RMIA, Narmann RG, Kammerman S, Ciotoli C, Reibman J. Duration of asthma and physiologic outcomes in elderly non-smokers. Am J Respir Crit Care Med 2000; 162: 1423-8.
[59] Sears MR. Consequences of long-term inflammation: the natural history of asthma. Clin Chest Med 2000; 21: 315-29.
[60] Zeiger RS, Dawson C, Weiss S. Relationship between duration of asthma and asthma severity among children in the childhood asthma management programme. J Allergy Clin Immunol 1999; 103: 376-87.
[61] Foroutan N, Habibi M, Salamzadeh J. Designing a new questionnaire to evaluate asthma morbidity. Canadian Society for Pharmaceutical Sciences.
8th Annual Symposium of Canadian Society for Pharmaceutical Sciences: accelerating drug discovery and development. Toronto, Canada; 2005, May 30- June 2, p.64.
[62] Jebrak G, Brugiere O, Uffredi ML. Impact of infections a chlamydia pneumonia infections on asthma. Presse Med 2000; 29: 1425-32.
[63] Reddel H, Ware S, Marks G, Salome C, Jenkins C, Woolcock A. Differences between asthma exacerbations and poor asthma control. Lancet
1999; 353: 364-9.
[64] Smith A, Nicholson K. Psychosocial factors, respiratory viruses and exacerbation of asthma. Psychoneuroendocrinology 2001; 26: 411-20.
[65] Gern JE, Busse WW. The role of viral infections in the natural history of asthma. J Allergy Clin Immunol 2000; 106: 201-12.
[66] Micillo E, Bianco A, D’Auria D, Mazzarella G, Abbate GF. Respiratory infections and asthma. Eur J Allergy Clin Immunol (suppl) 2000; 55: 42-5.
[67] Salamzadeh J, Kebriayeezadeh A, Shalchi M. Drug utilization review of anti-asthma drugs using Defined Daily Doses (DDD) in 28 provinces
of Iran during the years 2000-2002. In: Valizadeh H, Azarmi S, Ghobe Zarrin N, (editors). 9th Iranian Seminar of Pharmaceutical Sciences.
Abstracts of contributions; Tabriz, Iran, 2004 August 23-26: Tabriz University of Medical Sciences; p. 284.
[68] Fleming DM, Cross KW, Sunderland R, Ross, AM. Comparison of the seasonal patterns of asthma identified in general practitioners episodes, hospital admissions, and deaths. Thorax 2000; 55: 662-5.
[69] Stedman JR, Anderson HR, Atkinson RW, Maynard RL. Emergency hospital admissions for respiratory disorders attributable to summer time ozone episodes in Great Britain. Thorax 1997; 52: 958-63.
[70] National asthma council Australia (2005) Asthma management handbook [Online], 2002, [accessed April 4, 2005]. [Online] Available from URL: .
[71] British Thoracic Society, National Asthma Campaign, Royal College of Physicians of London, General Practitioner in Asthma Group, British Association of Accident and Emergency Medicine, British Paediatric Respiratory Society and Royal College of Paediatrics and Child Health; The British guidelines on asthma
management: 1995 review and position statement. Thorax (suppl 1), 1997; 52: S1-S21.
[72] British Medical Association and Royal Pharmaceutical Society of Great Britain (2005) British National Formulary (Number 49). Oxon: The Pharmaceutical Press, 2005.
[73] Tavakkoli A, Rees PJ. Drug treatment of asthma in the 1990s: Achievement and new strategies. Drugs 1999; 57: 1-8.
[74] Corrigan CJ. Asthma refractory to glucocorticoids: the role of newer immunosuppressants. Am J Respir Med 2002; 1; 47-54.
[75] Corrigan CJ, Shiner RJ, Shakur BH, Ind PW. Methotrexate therapy of oral corticosteroiddependent asthmatics reduces serum immunoglobulins: correlation with clinical response to therapy. Clin Exp Allergy 2005; 35: 579-84.
[76] Karagiannidis C, Ruckert B, Hense G, Willer G, Menz G, Blaser K, Schmidt-Weber CB. Distinct eukcocyte redistribution after glococorticoid treatment among difficult-to treat asthmatic patients. Scand J Immunol 2005; 61: 187-96.
[77] Girgis SI, Nwokeji A, Shakur BH, Ind PW, Shiner RJ. The effect of steroid-sparing response to low-dose methotrexate on bone metabolism in glucocorticoid-dependent asthmatics. Clin Chim Acta 2004; 341: 157-63.
[78] General practitioners in asthma group. GPIAG opinion sheet no. 3. CFC to HFA: the transition [Online], 2001 [accessed 2002 May 1, 2002]. Available from: URL: http:// www.gpiagasthma. org/Opinions/opinion3.htm.
[79] Schlaeppi M, Edwards K, Fuller RW, Sharma Ret al. Patient perception of the Diskcus inhaler: a comparison with the Turbuhaler inhaler. Br J Clin Pract 1996; 50: 14-9.
[80] Sharma RK, Edwards K, Hallet C, Fuller RW. Perception among paediatric patients of the Discus inhaler, a novel multidose powder inhaler for use in the treatment of asthma: comparison with the Turbuhaler inhaler. Clin Drug Invest 1996; 11:145-53.
[81] Levy M, Hilton S, Barnes G. Asthma at your fingertips. 3rd ed. London: National Asthma and Respiratory Training Centre; 2000. pp.14, 164, 169, 180, 212.
[82] Persson G, Olsson B, Soliman S. The impact of inspiratory effort on inspiratory flow through Turbuhaler in asthmatic patients. Eur Respir J 1997; 10: 681-4.
[83] Gottlieb S. Personalizsed medicine comes one step closer for asthma. Br Med J 2000; 321: 724.
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