Water Absorption of Chitosan, Collagen, and Chitosan/Collagen Blend Membranes Exposed to Gamma-Ray Irradiation Water Absorption of the Membranes Exposed to Irradiation
Iranian Journal of Pharmaceutical Sciences,
Vol. 14 No. 1 (2018),
15 January 2018
,
Page 57-66
https://doi.org/10.22037/ijps.v14.40672
Abstract
This study investigated the water absorption of chitosan, collagen, and chitosan/collagen blend membranes exposed to gamma-ray irradiation. These membranes were produced via the solvent evaporation method. All membranes then underwent irradiation at 15 or 25 kGy gamma-ray doses, while membranes without irradiation were used as controls. After immersing the membranes in distilled water for up to 180 min, water absorption was determined by calculating the percentage weight increase. The results demonstrated some changes in the water absorption curves with differing membranes and irradiation doses. However, after 60 min, all of the water absorption curves plateaued. With respect to membrane type, the chitosan membranes exhibited the highest water absorption; the blend displayed the lowest; and also the collagen was in the mid range. With the use of higher radiation doses, the chitosan membranes displayed lower water absorption, which was also true of the blend but not collagen membranes. To conclude, the water absorption of chitosan, collagen, and chitosan/collagen blend membranes with and without gamma-ray irradiation initially increased steadily and then plateaued. The water absorption values of the irradiated blend membranes were the lowest; however, the values were relatively steady.
- chitosan
- collagen
- gamma-ray
- irradiation
- water absorption
How to Cite
References
[2] Azuma K, Izumi R, Ozaki T. Chitin, chitosan and its derivatives for wound healing: old and new materials. J Funct Biomater (2015)6(1): 104-142.
[3] Mogosanu G.D and Gremezuscu A.M. Natural and synthetic polymers for wounds and burns dressing. Int J Pharm (2014)463(2): 127-136.
[4] Li P, Poon Y.F, Li W, Zhu H.Y, Yeap S.H, Cao Y, Qi X, Lamrani M, Beuerman R.W, Kang E.T, Mu Y, Li C.M, Chang M.W, Leong S.S.J, Chan-Park M.B. A polycationic antimicrobial and biocompatible hydrogel with microbe membrane suctioning ability. Nat Mater (2011)10(2):149–156.
[5] Casettari L, Vllasaliu D, Castagnino E, Illum L. PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical application. Polymer Scienc (2012) 37(5): 659-685.
[6] Fleck C.A and Simman R. Modern collagen wound dressings: function and purpose. J Am Col Certif Wound Spec (2010)2(3):50–54.
[7] Brett D. A Review of Collagen and Collagen-based Wound Dressing. Wound A Compedium of Clinical Research and Practice. Wounds (2008)20(12): 347-356.
[8] Fernandes L.L, Resende C.X, Tavares D.S, Soares G.A. Cytocompatibility of Chitosan and Collagen-Chitosan Scaffolds for Tissue Engineering. Polimers (2011)21:1-6.
[9] Ramasamy P and Shanmugam A. Characterization and wound healing property of collagen–chitosan film from Sepia kobiensis. Int J Biol Macromol (2015)74: 93-102.
[10] Delphi, L, Sepehri, H, Motewaseli, E, Khorramizadeh, M.R. Collagen extracted from persian gulf squid exhibits anti-cytotoxic properties of apple pectic treated cells: assessment in an in-vitro biassay. IJPH (2016)45(8):1054-1063.
[11] Mahboob, S. Isolation and characterization of collagen from fish waste material-skin, scales and fins of Catla catla and Cirrhinus mrigala. J Food Sci Technol (2015)52(7): 4296-4305.
[12] Techatanawat S, Surarit R, Suddhasthira T, Siribang-on P.K. Type I collagen extracted from rat-tail and bovine achilles tendon for dental application: a comparative study. Asian Biomedicine (2011)5(6): 787-798.
[13] Silvipriya K.S, Kumar K.K, Bhat A.R, Kumar B.D, John A, Iakshmanan P. Collagen: animal sources and biomedical application. JAPS (2015)5(3): 123-127.
[14] Gomez-Guillen M.C, Gimenez B, Lopez-Caballero M.E, Montero M.P. Functional and bioactive properties of collagen and gelatin from alternative sources: a review. Food Hydrocolloids (2011)25(8): 1813-1817.
[15] Zhang F, Wang A, Li Z, He S, Shao L. Preparation and characterization of collagen from freshwater fish scales. Food and Nutrition Sciences (2011)2: 818-823.
[16] Benhabiles M.S, Salah R, Lounici H, Drouiche N, Goosen M.F.A, Nameri N. Antibacterial activity of chitin, chitosan and its oligomers prepared from shrimp shell waste. Food Hydrocoloids (2012)29: 48-56.
[17] Makuuchi K and Cheng S. Radiation Processing Of Polymer Materials And Its Industrial Application. John Wiley & Sons, Inc: New York (2012).
[18] ISO 11137-2:2013. Sterilization of health care products-radiation: establishing the sterilization dose.
[19] Bajpai M, Bajpai S.K, Jyotishi P. Water absorption and moisture permeation properties of chitosan/poly(acrylamide-co-itaconic acid) IPC films. IJBM (2016)84: 1-9.
[20] Mazor E and Zilberman M. Effect of gamma-irradiation sterilization on the physical and mechanical properties of a hybrid wound dressing. Polym Adv Technol (2017)28: 41-52.
[21] Bano I, Ghauri M.A, Yasin T, Huang Q, Palaparthi A.S. Characterization and potential applications of gamma irradiated chitosan and its blends with poly(vinyl alcohol). IJBM (2014) 65: 81-88.
[22] Indrani D.J, Lukitowati F, Yulizar Y. Preparation of chitosan/collagen blend membranes for wound dressing: FTIR spectroscopy study and mechanical properties. In: IOP Conf. Series: Materials Science and Engineering 202 (2017) 012020. Proceeding of the 4th International Conference on Advanced Materials Science and Technology, Malang, Indonesia, September (2016).
[23] Indrani D.J., Lukitowati, Darwis D. Effect of gamma-ray irradiation on bacterial penetration power of chitosan/collagen blend membranes for wound dressing. JIDMR (2016)9(3): 202-206.
[24] Uriarte-Montoya M, Moscoso J, Jatomea M, Ortega H.S, Sandez O.R, Lopez J.L.C, Rios E.M, Brauer J.M.E. Jumbo squid (Dosidicus gigas) mantle collagen: extraction, characterization, and potential application in preparation of chitosan-collagen biofilms. Bioresource Technology (2010)101: 4212-4219.
[25] ASTM D570-98 (2010). Standart test method for water absorption of plastic.
[26] Ferapontov N.B, Tokmachev M.G, Gagarin A.N, Strusovskaya N.L, Khudyakova S.N. Influence of the environment on swelling of hydrophilic polymers. React Funct Polym (2013)73: 1137-1143.
[27] Long C, Li Y, Yu W, Li A. Adsorption characteristics of water vapor on the hypercrosslinked polymeric adsorbent. Chemical Engineering Journal (2012)180: 106-112.
[28] Sionkowska A, Wisniewski M, Skopinska J, Poggi G.F, Marsano E, Maxwell C.A, Wess T.J. Thermal and mechanical properties of UV irradiated collagen/chitosan thin films. Polymer Degradation and Stability (2006) 91:3026-3032.
[29] Test methods for primary wound dressing. Part 1: Aspects of absorbency. Section 3.3-Fluid Handling Capacity (absorbency plus moisture vapour transmission rate, liquid in contact). BS EN 13726-1 Section 3.3. British Standards Institution. 2002.
- Abstract Viewed: 480 times
- IJPS_Volume 14_Issue 1_Pages 57-66 Downloaded: 281 times