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  3. Vol. 5 No. 3 (2009): IJPS_Volume 5_Issue 3 (2009)
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Vol. 5 No. 3 (2009)

July 2009

Evaluation of Anti-inflammatory Activity of Methanolic Extractof Solanum nigrum(Solanaceae) Anti-inflammatory effect of Solanum nigrumLinn extract

  • Ganesan Arunachalam
  • Natesan Subramanian
  • Gururaja Perumal Pazhani
  • Manickam Karunanithi
  • Vellayutham Ravichandran

Iranian Journal of Pharmaceutical Sciences, Vol. 5 No. 3 (2009), 1 July 2009 , Page 151-156
https://doi.org/10.22037/ijps.v5.41210

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Abstract

The methanolic extract of whole plants of Solanum nigrumL. was investigated for anti-inflammatory activity on the experimental animal models. The methanolic extract at a concentration of 100 mg.kg-1and 200 mg.kg-1, p.o.showed the significant dose dependent anti-inflammatory activity in carrageenin and egg white induced hind paw oedema in rats. Anti-inflammatory activity of the tested extract was comparable with that of the standard drug indomethacin (10 mg.kg-1) and cyproheptadine (8mg.kg-1). The results lend support to the traditional use of Solanum nigrumin the treatment of inflammatory diseases

Keywords:
  • Anti-inflammatory activity
  • Solanum nigrum
  • Solanaceae
  • IJPS_Volume 5_Issue 3_Pages 151-156

How to Cite

Ganesan Arunachalam, Natesan Subramanian, Gururaja Perumal Pazhani, Manickam Karunanithi, & Vellayutham Ravichandran. (2009). Evaluation of Anti-inflammatory Activity of Methanolic Extractof Solanum nigrum(Solanaceae): Anti-inflammatory effect of Solanum nigrumLinn extract. Iranian Journal of Pharmaceutical Sciences, 5(3), 151–156. https://doi.org/10.22037/ijps.v5.41210
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References

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